Mississippi County, Missouri

A county in Missouri, ranked 76 of 115 by population.

CountyFIPS 29133

Within Missouri
Mississippi County, highlighted, with the areas around it. Boundaries generalised from the 2025 Census cartographic boundary file; neighbour fills carry no data. The dot marks Charleston, the county seat, located via the 2025 Census Gazetteer.

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Population
12,003
-130 (-1.1%) since 2020
Land area
411.6
square miles. A further 4.0% of the total area is water
Population density
29.2
people per square mile, computed rather than published
County seat
Charleston
Seat of county government.
Established
1845
180 years ago
Largest city
Charleston city
Population 4,731.

Sources: US Census Bureau, Population Estimates Program, Vintage 2025 Population Estimates, released 26 March 2026; US Census Bureau, Gazetteer Files, 2025 Gazetteer Files, released 10 September 2025; Wikidata (CC0), Wikidata. Retrieved 30 August 2026.

Satellite view

Aerial imagery of Mississippi County with its boundary drawn on top. A map shows you the shape; this shows you what is inside it, and which side of the line a place falls on.

Aerial view of Mississippi County, Missouri from the USGS National Map, with its boundary outlined
Imagery: USGS National Map, USGS Imagery Only, public domain, requested from USGS by your browser when you reach this point on the page, at 560 by 800 pixels. The boundary is the 2025 Census cartographic boundary file, reprojected to Web Mercator to match the imagery. You can also open the USGS National Map viewer.

Where Mississippi County ranks

Position among the 115 counties of Missouri, and among all 3,144 US counties and county-equivalents. Computed from the figures on this page.

MeasureValueIn MissouriNationally
Population12,00376th of 1152,280th of 3,144
Land area411.6 sq mi108th of 1152,456th of 3,144
Population density29.2 per sq mi61st of 1151,949th of 3,144
Median household income$48,160104th of 1152,866th of 3,143

Full data for Mississippi County

Every figure below is attributed to the Census Bureau product it came from, with the vintage of that product.
MeasureValueSource and vintage
Population12,003Vintage 2025 Population Estimates
Population in 202012,133Vintage 2025 Population Estimates
2020 estimates base?12,575Vintage 2025 Population Estimates
Land area411.6 sq mi2025 Gazetteer Files
Water area17.2 sq mi2025 Gazetteer Files
Total area428.8 sq mi2025 Gazetteer Files
Population density?29.2 per sq miComputed: Vintage 2025 estimates divided by 2025 Gazetteer land area
Median household income$48,160American Community Survey 2020-2024 5-Year Estimates
Median home value$109,000American Community Survey 2020-2024 5-Year Estimates
Median age41.1American Community Survey 2020-2024 5-Year Estimates
Households4,482American Community Survey 2020-2024 5-Year Estimates
Housing units5,272American Community Survey 2020-2024 5-Year Estimates

Sources: US Census Bureau, Population Estimates Program, Vintage 2025 Population Estimates, released 26 March 2026; US Census Bureau, Gazetteer Files, 2025 Gazetteer Files, released 10 September 2025; US Census Bureau, American Community Survey, American Community Survey 2020-2024 5-Year Estimates, released 29 January 2026. Population density is computed here, not published: it divides the Vintage 2025 population estimate by the 2025 Gazetteer land area, which are two different Census products. Retrieved 30 August 2026.

How the population changed

The Census Bureau publishes the components behind an estimate, not just the total. For the year to July 2025:

Births minus deaths
-32
141 births, 173 deaths
Net migration
+90
More people moved in than moved out.

Source: US Census Bureau, Population Estimates Program, Vintage 2025 Population Estimates, released 26 March 2026. Retrieved 30 August 2026.

The 7 areas bordering Mississippi County

Ordered by the length of the border actually shared, which the Census Bureau publishes in its county adjacency file and which no other county reference presents.

Bordering areaStateShared borderPopulation
New Madrid CountyMissouri27 mi15,086
Alexander CountyIllinois25 mi4,570
Scott CountyMissouri21 mi37,975
Carlisle CountyKentucky15 mi4,747
Hickman CountyKentucky15 mi4,372
Fulton CountyKentucky14 mi6,218
Ballard CountyKentucky3.9 mi7,594

Source: US Census Bureau, County Adjacency File, 2025 County Adjacency File, released 15 September 2025. Retrieved 30 August 2026.

All 115 counties of Missouri

Open the interactive Missouri county map, or jump straight to any of them.

Data on this page last rebuilt 30 August 2026. How these figures are produced.