Issaquena County, Mississippi

The least populous of Mississippi's 82 counties.

CountyFIPS 28055

Within Mississippi
Issaquena County, highlighted, with the areas around it. Boundaries generalised from the 2025 Census cartographic boundary file; neighbour fills carry no data. The dot marks Mayersville, the county seat, located via the 2025 Census Gazetteer.

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Population
1,263
-63 (-4.8%) since 2020
Land area
413
square miles. A further 6.4% of the total area is water
Population density
3.1
people per square mile, computed rather than published
County seat
Mayersville
Seat of county government.
Established
1844
181 years ago
Largest city
Mayersville town
Population 453.

Sources: US Census Bureau, Population Estimates Program, Vintage 2025 Population Estimates, released 26 March 2026; US Census Bureau, Gazetteer Files, 2025 Gazetteer Files, released 10 September 2025; Wikidata (CC0), Wikidata. Retrieved 30 August 2026.

Satellite view

Aerial imagery of Issaquena County with its boundary drawn on top. A map shows you the shape; this shows you what is inside it, and which side of the line a place falls on.

Aerial view of Issaquena County, Mississippi from the USGS National Map, with its boundary outlined
Imagery: USGS National Map, USGS Imagery Only, public domain, requested from USGS by your browser when you reach this point on the page, at 609 by 800 pixels. The boundary is the 2025 Census cartographic boundary file, reprojected to Web Mercator to match the imagery. You can also open the USGS National Map viewer.

Where Issaquena County ranks

Position among the 82 counties of Mississippi, and among all 3,144 US counties and county-equivalents. Computed from the figures on this page.

MeasureValueIn MississippiNationally
Population1,26382nd of 823,093rd of 3,144
Land area413 sq mi73rd of 822,448th of 3,144
Population density3.1 per sq mi82nd of 822,898th of 3,144
Median household income$31,42982nd of 823,136th of 3,143

Full data for Issaquena County

Every figure below is attributed to the Census Bureau product it came from, with the vintage of that product.
MeasureValueSource and vintage
Population1,263Vintage 2025 Population Estimates
Population in 20201,326Vintage 2025 Population Estimates
2020 estimates base?1,337Vintage 2025 Population Estimates
Land area413 sq mi2025 Gazetteer Files
Water area28.4 sq mi2025 Gazetteer Files
Total area441.4 sq mi2025 Gazetteer Files
Population density?3.1 per sq miComputed: Vintage 2025 estimates divided by 2025 Gazetteer land area
Median household income$31,429American Community Survey 2020-2024 5-Year Estimates
Median home value$110,800American Community Survey 2020-2024 5-Year Estimates
Median age49.8American Community Survey 2020-2024 5-Year Estimates
Households350American Community Survey 2020-2024 5-Year Estimates
Housing units421American Community Survey 2020-2024 5-Year Estimates

Sources: US Census Bureau, Population Estimates Program, Vintage 2025 Population Estimates, released 26 March 2026; US Census Bureau, Gazetteer Files, 2025 Gazetteer Files, released 10 September 2025; US Census Bureau, American Community Survey, American Community Survey 2020-2024 5-Year Estimates, released 29 January 2026. Population density is computed here, not published: it divides the Vintage 2025 population estimate by the 2025 Gazetteer land area, which are two different Census products. Retrieved 30 August 2026.

How the population changed

The Census Bureau publishes the components behind an estimate, not just the total. For the year to July 2025:

Births minus deaths
-9
2 births, 11 deaths
Net migration
-17
More people moved out than moved in.

Source: US Census Bureau, Population Estimates Program, Vintage 2025 Population Estimates, released 26 March 2026. Retrieved 30 August 2026.

The 6 areas bordering Issaquena County

Ordered by the length of the border actually shared, which the Census Bureau publishes in its county adjacency file and which no other county reference presents.

Bordering areaStateShared borderPopulation
East Carroll ParishLouisiana75 mi6,760
Warren CountyMississippi47 mi41,759
Sharkey CountyMississippi40 mi3,097
Washington CountyMississippi15 mi40,446
Yazoo CountyMississippi5.8 mi22,947
Chicot CountyArkansas0.5 mi9,107

Source: US Census Bureau, County Adjacency File, 2025 County Adjacency File, released 15 September 2025. Retrieved 30 August 2026.

All 82 counties of Mississippi

Open the interactive Mississippi county map, or jump straight to any of them.

Data on this page last rebuilt 30 August 2026. How these figures are produced.